Innovative Fetal Healthcare
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A healthy baby starts with knowing its DNA


papSeek is a safe, noninvasive procedure for fetal genetic testing that provides reliable information on the health of the mother and her baby.

The test can examine fetal genetics as early as 5 weeks of pregnancy with no risk to the mother and her developing baby.

The test provides information on the baby’s sex, genetic traits and potential inherited diseases such as Sickle Cell Disease and many others, so the family and their physician can prepare for the best possible health outcome for the baby.

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How the Test Works

1. Order a test kit online at, or ask your doctor

2. Bring kit to first prenatal visit with OB/GYN

3. OB/GYN conducts Pap test with cytobrush from kit


4. OB/GYN preserves sample for shipping


5. Mother or OB/GYN ships kit to laboratory with prepaid packaging

6. Results will be sent to OB/GYN for review with mother


The Science Behind the Test



It is possible to collect fetal cells with a routine Pap test because fetal cells will migrate from the placenta into the uterine tract.

The fetal cells make a unique protein not present on adult maternal cells. The fetal cells are captured with magnetic nanoparticles coated with antibodies against this unique fetal protein.

DNA in the fetal cells is purified and separated from any remaining maternal DNA. The fetal DNA can now be analyzed in great detail using various molecular testing approaches.



papSeek is the earliest (5 weeks) possible prenatal genetic test available to provide families with information on the status of the pregnancy.

papSeek uses a Pap smear, which is considered a safe procedure during pregnancy, compared to the invasive procedures, amniocentesis and chorionic villous sampling.

papSeek tests fetal DNA using next-generation sequencing that can identify sex and genetic markers for known diseases.

Knowing earlier how the baby will develop can help the physician manage the pregnancy, and the family feel reassured they are preparing for the best possible outcome for their baby.

Explore your baby's DNA today.


Better with Science!

papSeek and TRIC (trophoblast retrieval and isolation from the Cervix) are based on years of research that has been peer reviewed and published in professional journals.

Supported by the National Institute of Health, the technology is now being developed into products by the Detroit-based company, Advanced Reproductive Technology - ART. ART is supported by university and industry partners to ensure rapid clinical implementation to help families in need. This work is under constant development to even better inform families and their professional healthcare providers. 

Please read about our groundbreaking research by following this link.

If you are interested in news articles and podcasts on the topic please look here.

Ongoing Research

news coverage

If you have any questions please feel free to consult with your healthcare provider regarding any medical issues, and our FAQ page. You can also write to with questions about the technology.